Cobalt(II)-catalyzed asymmetric hydrosilylation of simple ketones using dipyridylphosphine ligands in air.
نویسندگان
چکیده
In the presence of PhSiH(3) as the hydride donor, catalytic amounts of non-racemic dipyridylphosphine and an easy-to-handle cobalt salt Co(OAc)(2)·4H(2)O formed in situ an effective catalyst system for the asymmetric reduction of a diverse range of aryl alkyl ketones with moderate-to-excellent enantioselectivities (up to 96% ee). This approach tolerated the handling of both catalyst and reactants under air without special precautions.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 9 16 شماره
صفحات -
تاریخ انتشار 2011